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Sexual Health

Vaccination And Sexual Health Beyond HPV

Several sexually transmissible infections have vaccines, and each works differently — some prevent infection, others prevent the disease that infection would otherwise cause.

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Vaccination is strongly associated with one infection in sexual health, but it is not the only one where immunisation is relevant. What each vaccine actually prevents differs.

Hepatitis B is transmitted sexually and vaccine-preventable

Hepatitis B is a blood-borne virus that transmits efficiently through sexual contact as well as through blood. It can establish long-term infection of the liver.

The vaccine has been in routine use for decades and is given as a course rather than a single dose, because the immune response builds across repeated exposures to the antigen.

In many countries it is now part of childhood immunisation, so younger adults may already be protected without recalling it. Sexual health services can check status where it matters.

Hepatitis A spreads by a different route

Hepatitis A is transmitted through faecal-oral contact, which includes some sexual practices. It causes an acute illness rather than chronic liver infection.

Outbreaks among men who have sex with men have occurred in several countries, and services in those settings routinely offer the vaccine as part of a wider sexual health package.

The route matters more than the label. A vaccine offered in a sexual health clinic is offered because of how the infection travels, not as a comment on anyone's behaviour.

Meningococcal vaccination has an indirect role

Some meningococcal bacteria are carried harmlessly in the throat and transmitted by close contact including kissing. Vaccines against certain groups have been used in outbreak responses.

There has also been interest in whether one such vaccine offers partial cross-protection against gonorrhoea, because the two organisms are closely related. This is an active area rather than settled practice.

Whether it is offered depends entirely on national policy, which differs between countries and is revised as evidence accumulates. Local services are the only reliable guide.

Why vaccines cannot cover everything

Vaccines work by presenting a stable target to the immune system. Organisms that change their surface proteins rapidly, or that hide inside cells, are much harder to target this way.

Some infections also fail to generate lasting natural immunity even after full recovery, which suggests the immune system does not have an obvious handle for a vaccine to exploit.

That is why several common sexually transmitted infections remain preventable only through barriers, testing and treatment rather than through immunisation.

How to find out what applies to you

Eligibility, schedules and which vaccines are funded vary by country, by age and sometimes by risk group, and these programmes are updated regularly.

A sexual health service or general practice can check what has already been given and what is recommended locally, which is more reliable than reasoning from general information.

Vaccination sits alongside testing rather than replacing it, since the infections without vaccines are precisely the ones that regular testing is designed to catch.

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Dr Ayesha Quraishi
Medical Editor, Wellness 69

Ayesha is a practising GP with a special interest in sexual and reproductive health. She has spent a career answering questions people apologise for asking.

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